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FIP1L1(E12)-PDGFRA(E12) Translocation

CBP20204D

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Introduction 
Format DNA
Description FIP1L1, factor interacting with PAPOLA and CPSF1, contributes to poly(A) site processing (PMID: 14749727). FIP1L1 fusions play an important role in the pathogenesis of leukemia (PMID: 24763514), including FIP1L1-PDGFRA in acute myeloid leukemia (PMID: 32269633, PMID: 31450116) and in myeloid/lymphoid neoplasms with eosinophilia (PMID: 31995156), and FIP1L1 fusions with ROS1 has been observed in spitzoid neoplasms (PMID: 31361613).
   
Technical Data 
Left Gene FIP1L1
Left Breakpoint Chr4:542****1:+
Right Gene PDGFRA
Right Breakpoint Chr4:551****8:+
Buffer Tris-EDTA
   
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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