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AI-Edigene? EGFR VIII (E2-E7del) Translocation

CBP20203D#

產(chǎn)品描述
產(chǎn)品數據庫
Introduction 
Format DNA
Description EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth. EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancerand colorectal cancer, and the EGFRvIII variant is commonly found in glioblastoma.
   
Technical Data 
Left Gene EGFR(E2)
Left Breakpoint chr7:55206313:+
Right Gene EGFR(E7)
Right Breakpoint ch2:55223325:+
%AF 50%
Buffer Tris-EDTA
   
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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