UMR-106（大鼠骨肉瘤細胞）
CBP60904
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| I. General information | |
| Synonyms: | UMR-106 |
| Background: | Both the original sarcoma and the cloned line were developed by T.J. Martin at the University of Sheffield. The UMR-106 cell line is a clonal derivative of a transplantable rat osteosarcoma that had been induced by injection of radiophosphorous (32P). |
| Species: | Rattus norvegicus, rat |
| Tissue: | bone |
| Disease: | osteosarcoma |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Culture Medium: |
DMEM+10%FBS UMR-106完全培養基，# CBP60904M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Receptor Expression: | parathyroid hormone (PTH); 1-25(OH)2D3 (bone resorbing steroid hormone) |
| Comments: | The cells are responsive to PTH, prostaglandins and bone resorbing steroids. The PTH responsiveness of UMR-106 is greater than that of the related cell line UMR-108 (ATCC CRL-1663). Activation of protein kinase C inhibits ATP induced increases in intracellular calcium levels. For more information, please contact Cobioer (4008-750-250). |
