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RAGE/HEK293

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I. Background
RAGE (receptor for advanced glycation endproducts) also called advanced glycosylation end product (AGE), is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
 
II. Introduction
Host Cell: HEK293
Expressed gene: RAGE
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: DMEM +10%FBS+2ug/ml puromycin
Storage: Liquid nitrogen
 
III. Description of Host Cell Line
Organism: Homo sapiens, human
Tissue: Embryonic kidney
Disease: Normal
Morphology: Epithelial
Growth Properties: Adherent
 
IV. Representative Data

 

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