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pCBRG- PPARg RE

CBV20075

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Introduction
Description: pPPARg RE-Luc is designed for monitoring the induction of peroxisome proliferator-activated receptor gamma.This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): Peroxisome proliferator-activated receptor gamma
Pathway profile:
Full Name: Peroxisome proliferator-activated receptor gamma
Cis response element: PPARg RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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