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pCBRG-GATA6 RE

CBV20032

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Introduction
Description: pGATA6 RE-Luc is designed for monitoring the induction of globin transcription factor 6.GATA-6, a zinc finger transcription factor, is important in the endodermal differentiation of organ tissues.It is also indicated in proper lung development by controlling the late differentiation stages of alveolar epithelium and aquaporin-5 promoter activation. Furthermore, GATA-6 has been linked to the production of LIF, a cytokine that encourages proliferation of endodermal embryonic stem cells and blocks early epiblast differentiation. If left unregulated in the developing embryo, this cytokine production and chemical signal contributes to the phenotypes discussed further below.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): GATA6
Pathway profile:
Full Name: globin transcription factor 6
Cis response element: GATA6 RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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