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pCBRG- YY1 RE

CBV20048

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Introduction
Description: pYY1 RE-Luc is designed for monitoring the induction of Yin Yang 1 responese element.YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. Hence, the YY in the name stands for "yin-yang." YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.YY1 promotes enhancer-promoter chromatin loops by forming dimers and promoting DNA interactions. Its disregulation disrupts enhancer-promoter loops and gene expression.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): Yin Yang 1
Pathway profile:
Full Name: Yin Yang 1
Cis response element: YY1 RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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