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FGFR2-AHCYL1/BaF3

CBP73267

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I. Introduction

Cell Line Name:

FGFR2-AHCYL1/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

 
II. Background

FGFR2-AHCYL1 results from the fusion of FGFR2 and AHCYL1, resulting in the ability to activate MAPK signaling and induce transformation of cells in culture and in animal models (PMID: 24122810). FGFR2-AHCYL1 has been identified in intrahepatic cholangiocarcinoma (PMID: 24122810).

 
III. Representative Data

1. WB of  FGFR2-AHCYL1/BaF3

2. Sanger of  FGFR2-AHCYL1/BaF3

3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 FGFR2-AHCYL1 Cells(C1).

 

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