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首頁(yè) /藥靶模型 /其他細胞 /Nuclear Receptor /ESR1[D538G]-GAL4 Luciferase Reporter HEK293

ESR1[D538G]-GAL4 Luciferase Reporter HEK293

CBPM0004

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I. Background
The estrogen receptor (ER/ESR1) is a member of the nuclear hormone receptor superfamily of ligand-activated transcription factors and is expressed in the majority of luminal breast cancers . Upon binding an estrogenic ligand, this transcription factor regulates the expression of genes required for cancer cell proliferation and survival.
 
II. Introduction
Host Cell: HEK293
Expressed gene: ESR1[D538G]-GAL4 Luciferase
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium:  
Storage: Liquid nitrogen
 
III. Description of Host Cell Line
Organism: Homo sapiens, Human
Tissue: Embryonic kidney
Disease: Normal
Morphology: Epithelial
Growth Properties: Adherent
 
IV. Representative Data
 

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