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CDKN2B Amplification Reference Standard

CBP40054

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Introduction  
Format Genomic DNA
Description CDKN2B, cyclin dependent kinase inhibitor 2B, regulates G1-S phase cell cycle arrest via specific inhibition of CDK4 and CDK6 kinases to function as a tumor suppressor (PMID: 27030077). CDKN2B deletion and/or promoter hypermethylation is commonly observed in acute lymphoblastic leukemia (PMID: 30635552, PMID: 30592434) and CDKN2B deletions have also been reported in liposarcoma (PMID: 21910158), renal cell carcinoma (PMID: 23898052), and glioma (PMID: 30558563).
   
Technical Data  
Copy number 8
Definition Amplification
   
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

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