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TP53 p.S241C Reference Standard

CBP10195

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Introduction 
Format Genomic DNA
Description TP53 S241C lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). S241C results in a loss of Tp53 transactivation activity in a yeast assay (PMID: 20407015), but has not been characterized in human cells and therefore, its effect on Tp53 protein function is unknown.
   
Technical Data 
DNA Change c.722C>G
AA Change p.S241C
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10709
Chr position(GRCh37) chr17:7577559
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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