CTNNB1 p.D32N Reference Standard
CBP10249
詢(xún) 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| Introduction | |
| Format | Genomic DNA |
| Description | CTNNB1 D32N lies within the ubiquitination recognition motif of the Ctnnb1 protein (PMID: 15064718). D32N confers a gain of function on the Ctnnb1 protein as demonstrated by a loss of ubiquitin ligase interaction leading to decreased ubiquitination and increased Ctnnb1-dependent transcription (PMID: 15064718, PMID: 11955436). |
| Technical Data | |
| DNA Change | c.94G>A |
| AA Change | p.D32N |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 32.09% |
| Transcript | ENST00000349496 |
| Cosmic ID | COSM5672 |
| Chr position(GRCh37) | chr3:41266097 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
